| Gene Information | |
|---|---|
| Gene Name | METTL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 276 |
| Protein Names | tRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.33) (Methyltransferase-like protein 1) (mRNA (guanine-N(7)-)-methyltransferase) (EC 2.1.1.-) (miRNA (guanine-N(7)-)-methyltransferase) (EC 2.1.1.-) (tRNA (guanine(46)-N(7))-methyltransferase) (tRNA(m7G46)-methyltransferase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000037897 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UBP6 |
| Gene Card | METTL1 |
| Uniprot ID | Q9UBP6 |
| Pfam | PF02390 |
| In ASD | no |
| Allosteric Prediction | no (-1.125477025) |
| Ortholog in Animals | Alpaca_ METTL1 ( ortholog_one2one ) Dog_ METTL1 ( ortholog_one2one ) GuineaPig_ METTL1 ( ortholog_one2one ) Macaque_ METTL1 ( ortholog_one2one ) Mouse_ Mettl1 ( ortholog_one2one ) Pig_ METTL1 ( ortholog_one2one ) Rat_ Mettl1 ( ortholog_one2one ) Rabbit_ METTL1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:10329009}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.005605(Rat);0.093333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3CKK (X-ray 1.55A ) 7OGJ (X-ray 1.59A ) 7PL1 (X-ray 1.85A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:15861136, ECO:0000269|PubMed:26751069}. |
| Mouse PG classification | NA |
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