| Gene Information | |
|---|---|
| Gene Name | SCTR |
| Organism | Homo sapiens (Human) |
| Gene Length | 440 |
| Protein Names | Secretin receptor (SCT-R) |
| Target Name | secretin receptor |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000080293 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P47872 |
| Gene Card | SCTR |
| Uniprot ID | P47872 |
| Pfam | PF00002; PF02793 |
| In ASD | yes |
| Allosteric Prediction | yes (1.000141136) |
| Ortholog in Animals | Alpaca_ SCTR ( ortholog_one2one ) Dog_ SCTR ( ortholog_one2one ) GuineaPig_ SCTR ( ortholog_one2one ) Macaque_ SCTR ( ortholog_one2one ) Mouse_ Sctr ( ortholog_one2one ) Pig_ SCTR ( ortholog_one2one ) Rat_ Sctr ( ortholog_one2one ) Rabbit_ SCTR ( ortholog_one2one ) |
| Ohnologs | GIPR, ADCYAP1R1, VIPR2, GHRHR, VIPR1, PTH2R |
| Paralogs | ADGRE3, ADGRL2, VIPR1, ADGRL4, ADGRE2, ADGRG4, ADGRD1, ADGRL3, GHRHR, PTH2R, ADGRE1, ADGRD2, ADGRL1, ADGRB3, EVA1C, ADGRG1, ADGRF5, ADGRA3, GLP2R, PTH1R, CALCR, ADGRF3, GIPR, ADGRA1, ADGRF1, ADCYAP1R1, ADGRG5, ADGRE5, CRHR2, ADGRB2, ADGRG6, GCGR, ADGRB1, ADGRG2, ADGRA2, ADGRF4, VIPR2, ADGRG7, CALCRL, ADGRG3, CRHR1, GLP1R |
| Tissue | duodenum, pancreas |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.033333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6WI9 (EM 4.30A ) 6WZG (EM 2.30A ) 7D3S (EM 2.90A ) |
| DBSNP | rs6726491 rs3731600 |
| Subcellular location [CC] | Cell membrane {ECO:0000250|UniProtKB:P23811}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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