Gene Information
Gene NameSCOT
OrganismHomo sapiens (Human)
Gene Length520
Protein NamesSuccinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (SCOT) (EC 2.8.3.5) (3-oxoacid CoA-transferase 1) (Somatic-type succinyl-CoA:3-oxoacid CoA-transferase) (SCOT-s) (Succinyl-CoA:3-oxoacid CoA transferase)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBP55809
Gene CardOXCT1
Uniprot IDP55809
PfamPF01144
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityAbundant in heart, followed in order by brain, kidney, skeletal muscle, and lung, whereas in liver it is undetectable. Expressed (at protein level) in all tissues (except in liver), most abundant in myocardium, then brain, kidney, adrenal glands, skeletal muscle and lung;
also detectable in leukocytes and fibroblasts. {ECO:0000269|PubMed:9380443}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.001680(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 3DLX  (X-ray  2.20A 
DBSNP rs75134564  rs267606930  rs201752548  rs121909302  rs121909303  rs368841359  rs727504063  rs886043862  rs121909301  rs121909300  rs1327401976 
Subcellular location [CC]Mitochondrion {ECO:0000250|UniProtKB:B2GV06}.
Mouse PG classificationNA
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