| Gene Information | |
|---|---|
| Gene Name | TFAP2A |
| Organism | Homo sapiens (Human) |
| Gene Length | 437 |
| Protein Names | Transcription factor AP-2-alpha (AP2-alpha) (AP-2 transcription factor) (Activating enhancer-binding protein 2-alpha) (Activator protein 2) (AP-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000137203 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P05549 |
| Gene Card | TFAP2A |
| Uniprot ID | P05549 |
| Pfam | PF03299 |
| In ASD | no |
| Allosteric Prediction | yes (0.405351911) |
| Ortholog in Animals | Alpaca_ TFAP2A ( ortholog_one2one ) Dog_ TFAP2A ( ortholog_one2one ) GuineaPig_ TFAP2A ( ortholog_one2one ) Macaque_ TFAP2A ( ortholog_one2one ) Mouse_ Tfap2a ( ortholog_one2one ) Pig_ TFAP2A ( ortholog_one2one ) Rat_ Tfap2a ( ortholog_one2one ) |
| Ohnologs | TFAP2C, TFAP2B, TFAP2D, TFAP2E |
| Paralogs | TFAP2C, TFAP2B, TFAP2E, TFAP2D |
| Tissue | placenta, skin, esophagus.mucosa, lower.leg.skin, suprapubic.skin |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs151344528 rs121909574 rs121909575 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:12586840}. |
| Mouse PG classification | NA |
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