| Gene Information | |
|---|---|
| Gene Name | PZP |
| Organism | Homo sapiens (Human) |
| Gene Length | 1482 |
| Protein Names | Pregnancy zone protein (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6) |
| Target Name | pregnancy zone protein |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000126838 ) |
| Evolutionary Stage | NA |
| AlphaFoldDB | P20742 |
| Gene Card | PZP |
| Uniprot ID | P20742 |
| Pfam | PF00207; PF07703; PF07677; PF01835; PF17791; PF17789; PF07678 |
| In ASD | no |
| Allosteric Prediction | yes (0.608675082) |
| Ortholog in Animals | Alpaca_ PZP ( ortholog_one2one ) GuineaPig_ Mug1 ( ortholog_many2many ) Macaque_ PZP ( ortholog_one2one ) Mouse_ Mug2 ( ortholog_many2many ) Mouse_ Gm7298 ( ortholog_many2many ) Mouse_ Mug1 ( ortholog_many2many ) Rat_ Cpamd8 ( ortholog_many2many ) Rat_ Mug2 ( ortholog_many2many ) Rat_ Mug1 ( ortholog_many2many ) |
| Ohnologs | NA |
| Paralogs | CPAMD8, A2M, C3, A2ML1, CD109, C5, C4B, C4A |
| Tissue | NA |
| Tissue Specificity | Plasma. Prominent constituent of late-pregnancy sera. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12230214 rs3213832 rs2277413 rs3213831 rs57006764 rs200477595 rs2377741 rs10842971 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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