| Gene Information | |
|---|---|
| Gene Name | SCN3B |
| Organism | Homo sapiens (Human) |
| Gene Length | 215 |
| Protein Names | Sodium channel subunit beta-3 |
| Target Name | sodium channel protein |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000166257 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9NY72 |
| Gene Card | SCN3B |
| Uniprot ID | Q9NY72 |
| Pfam | PF07686 |
| In ASD | no |
| Allosteric Prediction | no (-0.229028948) |
| Ortholog in Animals | Alpaca_ SCN3B ( ortholog_one2one ) Dog_ SCN3B ( ortholog_one2one ) GuineaPig_ SCN3B ( ortholog_one2one ) Macaque_ SCN3B ( ortholog_one2one ) Mouse_ Scn3b ( ortholog_one2one ) Pig_ SCN3B ( ortholog_one2one ) Rat_ Scn3b ( ortholog_one2one ) Rabbit_ SCN3B ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SCN1B |
| Tissue | brain, cerebral.cortex, hippocampus, hypothalamus, nucleus.accumbens, pituitary.gland |
| Tissue Specificity | Expressed in the atrium. {ECO:0000269|PubMed:21051419}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4L1D (X-ray 2.50A ) 7TJ8 (EM 3.20A ) 7TJ9 (EM 2.90A ) |
| DBSNP | rs587777558 rs121918282 rs587777555 rs35174956 rs587777556 rs587777557 rs375755770 |
| Subcellular location [CC] | Membrane; Single-pass type I membrane protein. |
| Mouse PG classification | HPG |
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