Gene Information
Gene NameMEF2
OrganismHomo sapiens (Human)
Gene Length507
Protein NamesMyocyte-specific enhancer factor 2A (Serum response factor-like protein 1)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ02078
Gene CardMEF2A
Uniprot IDQ02078
PfamPF12347; PF00319
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityIsoform MEF2 and isoform MEFA are expressed only in skeletal and cardiac muscle and in the brain. Isoform RSRFC4 and isoform RSRFC9 are expressed in all tissues examined. {ECO:0000269|PubMed:1516833, ECO:0000269|PubMed:1748287}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.047059(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1C7U  (NMR  1EGW  (X-ray  1.50A  1LEW  (X-ray  2.30A  3KOV  (X-ray  2.90A  3MU6  (X-ray  2.43A  3P57  (X-ray  2.19A  6BYY  (X-ray  2.30A  6BZ1  (X-ray  2.97A 
DBSNP rs121918530  rs121918529  rs121918531 
Subcellular location [CC]Nucleus {ECO:0000255|PROSITE-ProRule:PRU00251, ECO:0000269|PubMed:12691662, ECO:0000269|PubMed:16563226}.
Mouse PG classificationNA
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