| Gene Information | |
|---|---|
| Gene Name | SCML2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 700 |
| Protein Names | Sex comb on midleg-like protein 2 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000102098 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9UQR0 |
| Gene Card | SCML2 |
| Uniprot ID | Q9UQR0 |
| Pfam | PF02820; PF17208; PF00536; PF12140 |
| In ASD | no |
| Allosteric Prediction | no (-0.405747984) |
| Ortholog in Animals | Alpaca_ SCML2 ( ortholog_one2one ) Dog_ SCML2 ( ortholog_one2one ) Macaque_ SCML2 ( ortholog_one2one ) Mouse_ Scml2 ( ortholog_one2one ) Pig_ SCML2 ( ortholog_one2one ) Rabbit_ SCML2 ( ortholog_one2one ) |
| Ohnologs | SCMH1, SCML4 |
| Paralogs | SAMD11, SCMH1, SFMBT2, SAMD7, L3MBTL3, THAP10, PHC2, SAMD1, PHC3, PHC1, SFMBT1, SCML1, SAMD13, L3MBTL2, MBTD1, L3MBTL4, L3MBTL1, SCML4 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in placenta, thymus and testis. Detected at lower levels in brain, liver, skeletal muscle, pancreas and ovary. {ECO:0000269|PubMed:10331946}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);NULL(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1OI1 (X-ray 1.78A ) 2BIV (X-ray 1.70A ) 2MEM (NMR - ) 2VYT (X-ray 1.90A ) 4EDU (X-ray 2.58A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000305}. |
| Mouse PG classification | NA |
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