| Gene Information | |
|---|---|
| Gene Name | SCIN |
| Organism | Homo sapiens (Human) |
| Gene Length | 715 |
| Protein Names | Scinderin (Adseverin) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000006747 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9Y6U3 |
| Gene Card | SCIN |
| Uniprot ID | Q9Y6U3 |
| Pfam | PF00626 |
| In ASD | no |
| Allosteric Prediction | no (-0.052632633) |
| Ortholog in Animals | Alpaca_ SCIN ( ortholog_one2one ) Alpaca_ SCIN ( ortholog_one2many ) Dog_ SCIN ( ortholog_one2one ) GuineaPig_ SCIN ( ortholog_one2one ) Macaque_ SCIN ( ortholog_one2one ) Mouse_ Scin ( ortholog_one2one ) Pig_ SCIN ( ortholog_one2one ) Rat_ Scin ( ortholog_one2one ) Rabbit_ SCIN ( ortholog_one2one ) |
| Ohnologs | AVIL, CAPG, VIL1, VILL |
| Paralogs | VIL1, VILL, SVIL, CAPG, AVIL, FLII, GSN |
| Tissue | kidney, small.intestine |
| Tissue Specificity | Expressed in megakaryocytes. {ECO:0000269|PubMed:11568009}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3FG6 (X-ray 3.00A ) 5A1K (X-ray 2.90A ) 5A1M (X-ray 1.81A ) |
| DBSNP | rs2240572 rs35083013 rs17166250 rs35705332 rs1138957 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000305}. Cell projection, podosome {ECO:0000250|UniProtKB:Q60604}. |
| Mouse PG classification | NA |
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