| Gene Information | |
|---|---|
| Gene Name | SCGB3A1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 104 |
| Protein Names | Secretoglobin family 3A member 1 (Cytokine HIN-1) (High in normal 1) (Pneumo secretory protein 2) (PnSP-2) (Uteroglobin-related protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 244 ( ENSG00000161055 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q96QR1 |
| Gene Card | SCGB3A1 |
| Uniprot ID | Q96QR1 |
| Pfam | PF20490 |
| In ASD | no |
| Allosteric Prediction | no (-1.464938437) |
| Ortholog in Animals | Alpaca_ SCGB3A1 ( ortholog_one2one ) GuineaPig_ SCGB3A1 ( ortholog_one2one ) Macaque_ SCGB3A1 ( ortholog_one2one ) Mouse_ Scgb3a1 ( ortholog_one2one ) Pig_ SCGB3A1 ( ortholog_one2one ) Rat_ Scgb3a1 ( ortholog_one2one ) Rabbit_ SCGB3A1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SCGB3A2 |
| Tissue | lung, salivary.gland, minor.salivary.gland |
| Tissue Specificity | Highly expressed in lung and prostate (PubMed:11481438). Also found in mammary gland, spleen, pancreas, testis and liver (PubMed:11481438). Detected throughout the airway epithelium in lung, with highest expression in large airways (PubMed:12406855). Found in lung submucosal glands where it localizes to acinar and ductile cells (PubMed:12406855). Not detected in respiratory bronchioles, alveolar ducts or alveolar epithelium (PubMed:12406855). In mammary gland, specifically localizes to luminal epithelial cells (PubMed:11481438). {ECO:0000269|PubMed:11481438, ECO:0000269|PubMed:12406855}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:11481438}. |
| Mouse PG classification | NA |
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