| Gene Information | |
|---|---|
| Gene Name | SCARF2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 871 |
| Protein Names | Scavenger receptor class F member 2 (SRECRP-1) (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000244486 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q96GP6 |
| Gene Card | SCARF2 |
| Uniprot ID | Q96GP6 |
| Pfam | PF00053 |
| In ASD | no |
| Allosteric Prediction | no (-0.798627841) |
| Ortholog in Animals | Alpaca_ SCARF2 ( ortholog_one2one ) GuineaPig_ SCARF2 ( ortholog_one2one ) Macaque_ SCARF2 ( ortholog_one2one ) Mouse_ Scarf2 ( ortholog_one2one ) Pig_ SCARF2 ( ortholog_one2one ) Rat_ Scarf2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SCARF1, CRB2, CRB3 |
| Tissue | NA |
| Tissue Specificity | Predominantly expressed in endothelial cells. Expressed in heart, placenta, lung, kidney, spleen, small intestine and ovary. {ECO:0000269|PubMed:12154095}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs361566 rs387907086 rs2241230 rs12484828 rs759611 rs759612 rs874100 rs874101 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Mouse PG classification | HPG |
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