| Gene Information | |
|---|---|
| Gene Name | SCD |
| Organism | Homo sapiens (Human) |
| Gene Length | 359 |
| Protein Names | Stearoyl-CoA desaturase (hSCD1) (EC 1.14.19.1) (Acyl-CoA desaturase) (Delta(9)-desaturase) (Delta-9 desaturase) (Fatty acid desaturase) |
| Target Name | acyl-coa desaturase |
| Target Type | Successful target |
| Gene Age | 645 ( ENSG00000099194 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | O00767 |
| Gene Card | SCD |
| Uniprot ID | O00767 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | yes (0.325456231) |
| Ortholog in Animals | Alpaca_ SCD ( ortholog_one2one ) Dog_ SCD ( ortholog_one2one ) Macaque_ SCD ( ortholog_one2one ) Mouse_ Scd2 ( ortholog_one2many ) Mouse_ Scd4 ( ortholog_one2many ) Pig_ SCD ( ortholog_one2one ) Rat_ Scd2 ( ortholog_one2many ) Rat_ Scd4 ( ortholog_one2many ) |
| Ohnologs | SCD5 |
| Paralogs | SCD5 |
| Tissue | NA |
| Tissue Specificity | Detected in fetal liver, lung and brain. Highly expressed in adult adipose tissue, and at lower levels in adult brain and lung. {ECO:0000269|PubMed:15907797}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 4ZYO (X-ray 3.25A ) |
| DBSNP | rs2234970 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:15907797}; Multi-pass membrane protein {ECO:0000269|PubMed:18765284, ECO:0000305}. |
| Mouse PG classification | NA |
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