| Gene Information | |
|---|---|
| Gene Name | SUN1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 785 |
| Protein Names | SUN domain-containing protein 1 (Protein unc-84 homolog A) (Sad1/unc-84 protein-like 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000164828 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O94901 |
| Gene Card | SUN1 |
| Uniprot ID | O94901 |
| Pfam | PF18580; PF09387; PF07738 |
| In ASD | no |
| Allosteric Prediction | no (-0.568188878) |
| Ortholog in Animals | Alpaca_ SUN1 ( ortholog_one2many ) Dog_ SUN1 ( ortholog_one2one ) GuineaPig_ SUN1 ( ortholog_one2one ) Macaque_ SUN1 ( ortholog_one2one ) Mouse_ Sun1 ( ortholog_one2one ) Pig_ SUN1 ( ortholog_one2one ) Rat_ Sun1 ( ortholog_one2one ) |
| Ohnologs | SUN2 |
| Paralogs | SUN3, SPAG4, SUN5, SUN2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);0.050000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6R15 (X-ray 1.82A ) 6R16 (X-ray 2.75A ) 6R2I (X-ray 1.54A ) 7E34 (X-ray 3.19A ) |
| DBSNP | rs6461378 rs144929525 rs114701323 |
| Subcellular location [CC] | Nucleus inner membrane {ECO:0000269|PubMed:12958361, ECO:0000269|PubMed:16445915, ECO:0000269|PubMed:17132086, ECO:0000269|PubMed:18845190, ECO:0000269|PubMed:19933576}; Single-pass type II membrane protein {ECO:0000269|PubMed:12958361, ECO:0000269|PubMed:16445915, ECO:0000269|PubMed:17132086, ECO:0000269|PubMed:18845190, ECO:0000269|PubMed:19933576}. Note=At oocyte MI stage localized around the spindle, at MII stage localized to the spindle poles. {ECO:0000250|UniProtKB:Q9D666}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |