| Gene Information | |
|---|---|
| Gene Name | SCCRO |
| Organism | Homo sapiens (Human) |
| Gene Length | 259 |
| Protein Names | DCN1-like protein 1 (DCNL1) (DCUN1 domain-containing protein 1) (Defective in cullin neddylation protein 1-like protein 1) (Squamous cell carcinoma-related oncogene) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q96GG9 |
| Gene Card | DCUN1D1 |
| Uniprot ID | Q96GG9 |
| Pfam | PF03556 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in pancreas, kidney, placenta, brain and heart. Weakly or not expressed in liver, skeletal muscle and lung. Strongly overexpressed in thyroid tumors, bronchioloalveolar carcinomas, and malignant tissues of squamous cell carcinoma of the oral tongue. Not overexpressed in aggressive adrenocortical carcinomas. {ECO:0000269|PubMed:10777668}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.07(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3TDU (X-ray 1.50A ) 3TDZ (X-ray 2.00A ) 4P5O (X-ray 3.11A ) 5UFI (X-ray 2.58A ) 5V83 (X-ray 2.00A ) 5V86 (X-ray 1.37A ) 5V88 (X-ray 1.60A ) 6B5Q (X-ray 2.16A ) 6BG3 (X-ray 1.05A ) 6BG5 (X-ray 1.10A ) 6P5V (X-ray 1.40A ) 6P5W (X-ray 1.69A ) 6XOL (X-ray 2.39A ) 6XOM (X-ray 2.10A ) 6XON (X-ray 2.80A ) 6XOO (X-ray 2.06A ) 6XOP (X-ray 2.07A ) 6XOQ (X-ray 2.07A ) 7KWA (X-ray 1.57A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:25349211, ECO:0000269|PubMed:26906416}. Cytoplasm {ECO:0000269|PubMed:26906416}. Note=The ubiquitinated form is localized in the cytoplasm. {ECO:0000269|PubMed:30587576}. |
| Mouse PG classification | NA |
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