| Gene Information | |
|---|---|
| Gene Name | SCCA |
| Organism | Homo sapiens (Human) |
| Gene Length | 390 |
| Protein Names | Serpin B3 (Protein T4-A) (Squamous cell carcinoma antigen 1) (SCCA-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P29508 |
| Gene Card | SERPINB3 |
| Uniprot ID | P29508 |
| Pfam | PF00079 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Squamous cells. Expressed in some hepatocellular carcinoma (at protein level). {ECO:0000269|PubMed:14970861}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2ZV6 (X-ray 2.70A ) 4ZK0 (X-ray 2.15A ) 4ZK3 (X-ray 2.00A ) |
| DBSNP | rs3180227 rs1065205 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:10956412, ECO:0000269|PubMed:14970861}. Note=Seems to also be secreted in plasma by cancerous cells but at a low level. |
| Mouse PG classification | NA |
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