| Gene Information | |
|---|---|
| Gene Name | LRP1B |
| Organism | Homo sapiens (Human) |
| Gene Length | 4599 |
| Protein Names | Low-density lipoprotein receptor-related protein 1B (LRP-1B) (Low-density lipoprotein receptor-related protein-deleted in tumor) (LRP-DIT) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000168702 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | NA |
| Gene Card | LRP1B |
| Uniprot ID | Q9NZR2 |
| Pfam | PF12662; PF16472; PF00008; PF07645; PF00057; PF00058 |
| In ASD | no |
| Allosteric Prediction | no (-0.644807059) |
| Ortholog in Animals | Alpaca_ LRP1B ( ortholog_one2one ) Dog_ LRP1B ( ortholog_one2one ) GuineaPig_ LRP1B ( ortholog_one2one ) Macaque_ LRP1B ( ortholog_one2one ) Mouse_ Lrp1b ( ortholog_one2one ) Pig_ LRP1B ( ortholog_one2one ) Rat_ Lrp1b ( ortholog_one2one ) Rabbit_ LRP1B ( ortholog_one2one ) |
| Ohnologs | LRP1 |
| Paralogs | LDLR, LRP12, LRP2, EGF, LRP1, VLDLR, LRP4, LRP5, NID2, LRP6, LRP3, LRP8, LRP10, NID1 |
| Tissue | NA |
| Tissue Specificity | Expressed in thyroid gland and in salivary gland, as well as in adult and fetal brain. {ECO:0000269|PubMed:11384978}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12990449 rs34488772 rs371536401 rs1878740 rs35546150 rs17386226 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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