| Gene Information | |
|---|---|
| Gene Name | SCAPER |
| Organism | Homo sapiens (Human) |
| Gene Length | 1400 |
| Protein Names | S phase cyclin A-associated protein in the endoplasmic reticulum (S phase cyclin A-associated protein in the ER) (Zinc finger protein 291) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000140386 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9BY12 |
| Gene Card | SCAPER |
| Uniprot ID | Q9BY12 |
| Pfam | PF16501 |
| In ASD | no |
| Allosteric Prediction | no (-1.072707237) |
| Ortholog in Animals | Alpaca_ SCAPER ( ortholog_one2one ) Dog_ SCAPER ( ortholog_one2one ) GuineaPig_ SCAPER ( ortholog_one2one ) Macaque_ SCAPER ( ortholog_one2one ) Mouse_ Scaper ( ortholog_one2one ) Pig_ SCAPER ( ortholog_one2one ) Rat_ Scaper ( ortholog_one2one ) Rabbit_ SCAPER ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed with high expression in testis. Isoform 1 is detected in various tissues, including retina, fetal and adult brain. Isoform 2 is expressed in the retina at high levels, and in the brain at very low levels (PubMed:28794130). {ECO:0000269|PubMed:17698606, ECO:0000269|PubMed:28794130}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1607017 rs3743176 rs3743176 rs1305542291 |
| Subcellular location [CC] | Endoplasmic reticulum {ECO:0000269|PubMed:17698606}. Nucleus {ECO:0000269|PubMed:17698606}. Note=Predominantly located in the endoplasmic reticulum, only a small portion is detected in the nucleus. |
| Mouse PG classification | NA |
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