| Gene Information | |
|---|---|
| Gene Name | TRPC3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 921 |
| Protein Names | Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (TRP-3) (hTrp-3) (hTrp3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000138741 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q13507 |
| Gene Card | TRPC3 |
| Uniprot ID | Q13507 |
| Pfam | PF12796; PF00520; PF08344 |
| In ASD | yes |
| Allosteric Prediction | yes (1.00039094) |
| Ortholog in Animals | Alpaca_ TRPC3 ( ortholog_one2one ) Dog_ TRPC3 ( ortholog_one2one ) GuineaPig_ TRPC3 ( ortholog_one2one ) Macaque_ TRPC3 ( ortholog_one2one ) Mouse_ Trpc3 ( ortholog_one2one ) Pig_ TRPC3 ( ortholog_one2one ) Rat_ Trpc3 ( ortholog_one2one ) Rabbit_ TRPC3 ( ortholog_one2one ) |
| Ohnologs | TRPC7, TRPC6 |
| Paralogs | TRPC7, TRPC6, TRPC1, TRPC5, TRPC4 |
| Tissue | NA |
| Tissue Specificity | Expressed predominantly in brain and at much lower levels in ovary, colon, small intestine, lung, prostate, placenta and testis. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5ZBG (EM 4.36A ) 6CUD (EM 3.30A ) 6D7L (EM 4.00A ) 6DJS (EM 5.80A ) 7DXB (EM 2.70A ) 7DXC (EM 3.06A ) 7DXD (EM 3.90A ) 7DXE (EM 3.20A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | HPG |
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