| Gene Information | |
|---|---|
| Gene Name | SCAMP5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 235 |
| Protein Names | Secretory carrier-associated membrane protein 5 (Secretory carrier membrane protein 5) (hSCAMP5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000198794 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8TAC9 |
| Gene Card | SCAMP5 |
| Uniprot ID | Q8TAC9 |
| Pfam | PF04144 |
| In ASD | no |
| Allosteric Prediction | no (-0.88069519) |
| Ortholog in Animals | Alpaca_ SCAMP5 ( ortholog_one2one ) Dog_ SCAMP5 ( ortholog_one2one ) GuineaPig_ SCAMP5 ( ortholog_one2one ) Macaque_ SCAMP5 ( ortholog_one2one ) Mouse_ Scamp5 ( ortholog_one2one ) Pig_ SCAMP5 ( ortholog_one2one ) Rat_ Scamp5 ( ortholog_one2one ) Rabbit_ SCAMP5 ( ortholog_one2one ) |
| Ohnologs | SCAMP1, SCAMP3 |
| Paralogs | SCAMP4, SCAMP3, SCAMP2, SCAMP1 |
| Tissue | NA |
| Tissue Specificity | Expressed both by neuronal and non-neuronal tissues. Expressed in brain, stomach, thyroid, spinal cord, lymph node, trachea, adrenal gland, bone marrow and in the different parts of brain. In thyroid tissues, it is expressed by the follicular epithelial cells. In the adrenal gland tissues it is detected in the zona fasciculata of the cortex region (at protein level). {ECO:0000269|PubMed:19234194}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Mainly localizes in Golgi apparatus membrane. Upon calcium-triggered exocytosis, it translocates to the cell membrane. Highly enriched in synaptic vesicles (By similarity). {ECO:0000250}. |
| Mouse PG classification | NA |
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