Gene Information
Gene NameSCAI
OrganismHomo sapiens (Human)
Gene Length606
Protein NamesProtein SCAI (Suppressor of cancer cell invasion protein)
Target NameNA
Target TypeNA
Gene Age987 ( ENSG00000173611 )
Evolutionary StageEukaryota
AlphaFoldDBQ8N9R8
Gene CardSCAI
Uniprot IDQ8N9R8
PfamPF12070
In ASDno
Allosteric Predictionno (-0.919994504)
Ortholog in AnimalsAlpaca_ SCAI ( ortholog_one2one )
Dog_ SCAI ( ortholog_one2one )
GuineaPig_ SCAI ( ortholog_one2one )
Macaque_ SCAI ( ortholog_one2one )
Mouse_ Scai ( ortholog_one2one )
Pig_ SCAI ( ortholog_one2one )
Rat_ Scai ( ortholog_one2one )
Rabbit_ SCAI ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs589292 
Subcellular location [CC]Membrane {ECO:0000305};
Single-pass membrane protein {ECO:0000305}. Nucleus {ECO:0000269|PubMed:19350017}. Cytoplasm {ECO:0000269|PubMed:19350017}. Note=Nuclear localization is required for inhibition of MRTFA. {ECO:0000250}.
Mouse PG classificationNA
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