| Gene Information | |
|---|---|
| Gene Name | SCAF1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1312 |
| Protein Names | Splicing factor, arginine/serine-rich 19 (SR-related C-terminal domain-associated factor 1) (SR-related and CTD-associated factor 1) (SR-related-CTD-associated factor) (SCAF) (Serine arginine-rich pre-mRNA splicing factor SR-A1) (SR-A1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000126461 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9H7N4 |
| Gene Card | SCAF1 |
| Uniprot ID | Q9H7N4 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.106064964) |
| Ortholog in Animals | Alpaca_ SCAF1 ( ortholog_one2one ) Dog_ SCAF1 ( ortholog_one2one ) GuineaPig_ SCAF1 ( ortholog_one2one ) Macaque_ SCAF1 ( ortholog_one2one ) Mouse_ Scaf1 ( ortholog_one2one ) Pig_ SCAF1 ( ortholog_one2one ) Rat_ Scaf1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SCAF11, PHRF1 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Highly expressed in fetal brain and liver, poorly expressed in salivary gland, heart, skin and ovary. Expressed in colorectal carcinomas and ovarian cancers. Overexpressed in colorectal carcinomas as compared to normal colonic mucosa. {ECO:0000269|PubMed:11461075, ECO:0000269|PubMed:15493872, ECO:0000269|PubMed:16631123, ECO:0000269|PubMed:17132108}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3745470 rs2304208 |
| Subcellular location [CC] | Nucleus {ECO:0000305}. |
| Mouse PG classification | NA |
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