| Gene Information | |
|---|---|
| Gene Name | NEURL3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 555 |
| Protein Names | E3 ubiquitin-protein ligase NEURL1B (EC 2.3.2.27) (Neuralized-2) (NEUR2) (Neuralized-like protein 1B) (Neuralized-like protein 3) (RING-type E3 ubiquitin transferase NEURL1B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000163121 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | A8MQ27 |
| Gene Card | NEURL1B |
| Uniprot ID | A8MQ27 |
| Pfam | PF07177 |
| In ASD | no |
| Allosteric Prediction | no (-1.659906688) |
| Ortholog in Animals | Alpaca_ NEURL3 ( ortholog_one2one ) Dog_ NEURL3 ( ortholog_one2one ) GuineaPig_ NEURL3 ( ortholog_one2one ) Macaque_ NEURL3 ( ortholog_one2one ) Mouse_ Neurl3 ( ortholog_one2one ) Pig_ NEURL3 ( ortholog_one2one ) Rat_ Neurl3 ( ortholog_one2one ) Rabbit_ NEURL3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NEURL1B, NEURL1, NEURL4 |
| Tissue | salivary.gland, pancreas |
| Tissue Specificity | Highest expression in brain, prostate and small intestine. In the brain the levels are higher in fetal than in adult stage. In the adult brain the highest levels are detected in the olfactory system, cerebellar cortex, optic nerve and the frontal lobe. {ECO:0000269|PubMed:19723503}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.072727(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:19723503}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |