| Gene Information | |
|---|---|
| Gene Name | CYSLTR2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 346 |
| Protein Names | Cysteinyl leukotriene receptor 2 (CysLTR2) (G-protein coupled receptor GPCR21) (hGPCR21) (G-protein coupled receptor HG57) (HPN321) |
| Target Name | cysteinyl leukotriene receptor 2 |
| Target Type | NA |
| Gene Age | 55 ( ENSG00000152207 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9NS75 |
| Gene Card | CYSLTR2 |
| Uniprot ID | Q9NS75 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | yes (1.092853743) |
| Ortholog in Animals | Alpaca_ CYSLTR2 ( ortholog_one2one ) Dog_ CYSLTR2 ( ortholog_one2one ) GuineaPig_ CYSLTR2 ( ortholog_one2one ) Macaque_ CYSLTR2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | GPR20, LPAR4, LPAR6, P2RY10, GPR35, GPR55, F2RL2, P2RY8, F2RL1, F2R, F2RL3, CYSLTR1, GPR18, GPR17, GPR65, GPR4 |
| Tissue | placenta |
| Tissue Specificity | Widely expressed, with highest levels in the heart, placenta, spleen, peripheral blood leukocytes and adrenal gland. In lung, expressed in the interstitial macrophages, and slightly in smooth muscle cells. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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