| Gene Information | |
|---|---|
| Gene Name | IGSF12 |
| Organism | Homo sapiens (Human) |
| Gene Length | 299 |
| Protein Names | CMRF35-like molecule 8 (CLM-8) (CD300 antigen-like family member A) (CMRF-35-H9) (CMRF35-H9) (CMRF35-H) (IRC1/IRC2) (Immunoglobulin superfamily member 12) (IgSF12) (Inhibitory receptor protein 60) (IRp60) (NK inhibitory receptor) (CD antigen CD300a) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9UGN4 |
| Gene Card | CD300A |
| Uniprot ID | Q9UGN4 |
| Pfam | PF07686 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes. {ECO:0000269|PubMed:10540326, ECO:0000269|PubMed:16339535, ECO:0000269|PubMed:9701027}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2Q87 (X-ray 1.70A ) |
| DBSNP | rs2272111 |
| Subcellular location [CC] | Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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