| Gene Information | |
|---|---|
| Gene Name | SAT1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 701 |
| Protein Names | Sulfate anion transporter 1 (SAT-1) (Solute carrier family 26 member 1) |
| Target Name | diamine acetyltransferase 1 |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000130066 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q9H2B4 |
| Gene Card | SLC26A1 |
| Uniprot ID | Q9H2B4 |
| Pfam | PF01740; PF00916 |
| In ASD | yes |
| Allosteric Prediction | no (-0.542589642) |
| Ortholog in Animals | Dog_ SAT1 ( ortholog_one2one ) GuineaPig_ SAT1 ( ortholog_one2one ) Macaque_ SAT1 ( ortholog_one2one ) Mouse_ Sat1 ( ortholog_one2one ) Pig_ SAT1 ( ortholog_one2one ) Rat_ Sat1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SATL1, SAT2 |
| Tissue | NA |
| Tissue Specificity | Expressed most abundantly in the kidney and liver, with lower levels in the pancreas, testis, brain, small intestine, colon, and lung. {ECO:0000269|PubMed:12713736}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs142573758 rs139024319 rs148832260 rs3796622 |
| Subcellular location [CC] | Cell membrane {ECO:0000250|UniProtKB:P58735}; Multi-pass membrane protein {ECO:0000255}. Basolateral cell membrane {ECO:0000250|UniProtKB:P45380}. |
| Mouse PG classification | NA |
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