| Gene Information | |
|---|---|
| Gene Name | VPS26A |
| Organism | Homo sapiens (Human) |
| Gene Length | 327 |
| Protein Names | Vacuolar protein sorting-associated protein 26A (Vesicle protein sorting 26A) (hVPS26) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000122958 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O75436 |
| Gene Card | VPS26A |
| Uniprot ID | O75436 |
| Pfam | PF03643 |
| In ASD | no |
| Allosteric Prediction | no (-0.833747169) |
| Ortholog in Animals | Alpaca_ VPS26A ( ortholog_one2one ) Dog_ VPS26A ( ortholog_one2one ) GuineaPig_ VPS26A ( ortholog_one2one ) Macaque_ VPS26A ( ortholog_one2one ) Mouse_ Vps26a ( ortholog_one2one ) Pig_ VPS26A ( ortholog_one2one ) Rat_ Vps26a ( ortholog_one2one ) Rabbit_ VPS26A ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | VPS26B, VPS26C |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001578(Rat);0.005263(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2FAU (X-ray 2.10A ) 5F0J (X-ray 2.70A ) 5F0L (X-ray 3.20A ) 5F0M (X-ray 3.10A ) 5F0P (X-ray 2.78A ) 7BLO (EM 9.50A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:15078903}. Endosome membrane {ECO:0000269|PubMed:22431521}; Peripheral membrane protein {ECO:0000250|UniProtKB:P40336}. Early endosome {ECO:0000269|PubMed:15078903, ECO:0000269|PubMed:16190980, ECO:0000269|PubMed:16732284, ECO:0000269|PubMed:20682791}. Note=Localizes to tubular profiles adjacent to endosomes (PubMed:15078903). Predominantly found in early not late endosomes (By similarity). {ECO:0000250|UniProtKB:P40336}. |
| Mouse PG classification | NA |
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