Gene Information
Gene NamePSMB8
OrganismHomo sapiens (Human)
Gene Length276
Protein NamesProteasome subunit beta type-8 (EC 3.4.25.1) (Low molecular mass protein 7) (Macropain subunit C13) (Multicatalytic endopeptidase complex subunit C13) (Proteasome component C13) (Proteasome subunit beta-5i) (Really interesting new gene 10 protein)
Target Nameproteasome subunit beta type-8
Target TypeNA
Gene Age544 ( ENSG00000204264 )
3 ( ENSG00000206298 )
3 ( ENSG00000226201 )
3 ( ENSG00000230034 )
3 ( ENSG00000230669 )
3 ( ENSG00000231631 )
3 ( ENSG00000235715 )
3 ( ENSG00000236443 )
Evolutionary StageCellular_organisms
AlphaFoldDBP28062
Gene CardPSMB8
Uniprot IDP28062
PfamPF00227
In ASDno
Allosteric Predictionno (-0.329090562)
Ortholog in AnimalsAlpaca_ PSMB8 ( ortholog_one2one )
GuineaPig_ PSMB8 ( ortholog_one2one )
Mouse_ Psmb8 ( ortholog_one2one )
Pig_ PSMB8 ( ortholog_one2one )
Rat_ Psmb8 ( ortholog_one2one )
Rabbit_ PSMB8 ( ortholog_one2one )
OhnologsPSMB5
ParalogsPSMB11, PSMA7, PSMA6, PSMA3, PSMB5, PSMA4, PSMB4, PSMB6, PSMA8, PSMA5, PSMA2, PSMB2, PSMB7, PSMB1, PSMA1, PSMB9, PSMB10, PSMB3
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.566143(Rat);0.250941(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 5L5A  (X-ray  2.40A  )  5L5B  (X-ray  2.80A  )  5L5D  (X-ray  2.80A  )  5L5E  (X-ray  2.90A  )  5L5F  (X-ray  2.50A  )  5L5H  (X-ray  2.60A  )  5L5I  (X-ray  2.90A  )  5L5J  (X-ray  2.90A  )  5L5O  (X-ray  2.60A  )  5L5P  (X-ray  2.80A  )  5L5Q  (X-ray  2.80A  )  5L5R  (X-ray  2.90A  )  5L5S  (X-ray  2.60A  )  5L5T  (X-ray  2.90A  )  5L5U  (X-ray  2.60A  )  5L5V  (X-ray  2.70A  )  5LTT  (X-ray  2.70A  )  5M2B  (X-ray  2.70A  )  6AVO  (EM  3.80A  )  6E5B  (X-ray  2.77A  )  7AWE  (X-ray  2.29A  )  7B12  (X-ray  2.43A  ) 
DBSNP rs114772012  rs2071543  rs17220206  rs748082671  rs1554239543  rs387906680 
Subcellular location [CC]Cytoplasm {ECO:0000255|PROSITE-ProRule:PRU00809}. Nucleus {ECO:0000250}.
Mouse PG classificationLPG
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