| Gene Information | |
|---|---|
| Gene Name | SAS6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 657 |
| Protein Names | Spindle assembly abnormal protein 6 homolog (HsSAS-6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q6UVJ0 |
| Gene Card | SASS6 |
| Uniprot ID | Q6UVJ0 |
| Pfam | PF16531; PF18594 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6YS4 (X-ray 2.11A ) 6Z4A (X-ray 1.46A ) |
| DBSNP | rs876661307 rs13375867 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:15665853, ECO:0000269|PubMed:24107630, ECO:0000269|PubMed:31722219}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:15572125, ECO:0000269|PubMed:15665853, ECO:0000269|PubMed:17681131}. Note=Component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells that can generate more than 100 centrioles (By similarity). Component of the centrosome. Associated only transiently with nascent procentrioles during centriole biogenesis. {ECO:0000250|UniProtKB:Q80UK7}. |
| Mouse PG classification | NA |
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