| Gene Information | |
|---|---|
| Gene Name | SARS1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 514 |
| Protein Names | Serine--tRNA ligase, cytoplasmic (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000031698 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P49591 |
| Gene Card | SARS1 |
| Uniprot ID | P49591 |
| Pfam | PF02403; PF00587 |
| In ASD | no |
| Allosteric Prediction | no (-0.090468345) |
| Ortholog in Animals | Alpaca_ SARS1 ( ortholog_one2one ) Dog_ SARS1 ( ortholog_one2one ) GuineaPig_ SARS1 ( ortholog_one2one ) Macaque_ SARS1 ( ortholog_one2one ) Mouse_ Sars ( ortholog_one2one ) Pig_ SARS1 ( ortholog_one2one ) Rat_ Sars1 ( ortholog_one2one ) Rabbit_ SARS1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SARS2 |
| Tissue | NA |
| Tissue Specificity | Brain. {ECO:0000269|PubMed:28236339}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.00625(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3VBB (X-ray 2.89A ) 4L87 (X-ray 2.90A ) 4RQE (X-ray 4.00A ) 4RQF (X-ray 3.50A ) |
| DBSNP | rs1553178049 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:22353712, ECO:0000269|PubMed:28236339}. Nucleus {ECO:0000269|PubMed:22353712}. Note=Predominantly cytoplasmic, but a minor proportion is also found in the nucleus. {ECO:0000269|PubMed:22353712}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |