| Gene Information | |
|---|---|
| Gene Name | SAR1B |
| Organism | Homo sapiens (Human) |
| Gene Length | 198 |
| Protein Names | GTP-binding protein SAR1b (GTP-binding protein B) (GTBPB) |
| Target Name | gtp-binding protein sar1b |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000152700 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9Y6B6 |
| Gene Card | SAR1B |
| Uniprot ID | Q9Y6B6 |
| Pfam | PF00025 |
| In ASD | no |
| Allosteric Prediction | no (-0.273548518) |
| Ortholog in Animals | Alpaca_ SAR1B ( ortholog_one2one ) Dog_ SAR1B ( ortholog_one2one ) GuineaPig_ SAR1B ( ortholog_one2one ) Macaque_ SAR1B ( ortholog_one2one ) Mouse_ Sar1b ( ortholog_one2one ) Pig_ SAR1B ( ortholog_one2one ) Rabbit_ SAR1B ( ortholog_one2one ) |
| Ohnologs | SAR1A |
| Paralogs | ARL5C, ARF4, ARL10, ARL16, ARL2, ARFRP1, ARL17B, ARL17A, ARF3, ARF1, ARL1, ARL8B, TRIM23, ARL4D, ARL9, ARL14, ARL4A, ARL6, ARL13B, ARL13A, ARL15, ARL11, ARL5A, ARF5, ARL3, ARL8A, ARF6, ARL4C, ARL5B, SAR1A |
| Tissue | NA |
| Tissue Specificity | Expressed in many tissues including small intestine, liver, muscle and brain. {ECO:0000269|PubMed:12692552}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs121917846 rs1254114609 rs28942109 rs28942110 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9QVY3}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9QVY3}. Golgi apparatus, Golgi stack membrane {ECO:0000250|UniProtKB:Q9QVY3}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9QVY3}. Note=Associated with the endoplasmic reticulum and Golgi stacks, in particular in the juxta-nuclear Golgi region. {ECO:0000250|UniProtKB:Q9QVY3}. |
| Mouse PG classification | NA |
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