| Gene Information | |
|---|---|
| Gene Name | SAP30L |
| Organism | Homo sapiens (Human) |
| Gene Length | 183 |
| Protein Names | Histone deacetylase complex subunit SAP30L (HCV non-structural protein 4A-transactivated protein 2) (Sin3 corepressor complex subunit SAP30L) (Sin3-associated protein p30-like) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000164576 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9HAJ7 |
| Gene Card | SAP30L |
| Uniprot ID | Q9HAJ7 |
| Pfam | PF13867; PF13866 |
| In ASD | no |
| Allosteric Prediction | no (-0.827138101) |
| Ortholog in Animals | Alpaca_ SAP30L ( ortholog_one2one ) Dog_ SAP30L ( ortholog_one2one ) GuineaPig_ SAP30L ( ortholog_one2one ) Macaque_ SAP30L ( ortholog_one2one ) Mouse_ Sap30l ( ortholog_one2one ) Pig_ SAP30L ( ortholog_one2one ) Rat_ Sap30l ( ortholog_one2one ) Rabbit_ SAP30L ( ortholog_one2one ) |
| Ohnologs | SAP30 |
| Paralogs | SAP30 |
| Tissue | NA |
| Tissue Specificity | Detected in brain and ovary, and at lower levels in heart, small intestine, lung, kidney, skeletal muscle, stomach and spleen (at protein level) (PubMed:18070604). Ubiquitous; expressed in all tissues tested with highest levels in testis (PubMed:14680513). {ECO:0000269|PubMed:14680513, ECO:0000269|PubMed:18070604}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2N1U (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | [Isoform 1]: Nucleus, nucleolus {ECO:0000269|PubMed:14680513, ECO:0000269|PubMed:16820529, ECO:0000269|PubMed:18070604, ECO:0000269|PubMed:19015240}.; [Isoform 2]: Nucleus, nucleolus {ECO:0000269|PubMed:18070604}.; [Isoform 3]: Nucleus, nucleolus {ECO:0000269|PubMed:18070604}. |
| Mouse PG classification | NA |
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