| Gene Information | |
|---|---|
| Gene Name | SAMD1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 538 |
| Protein Names | Sterile alpha motif domain-containing protein 1 (SAM domain-containing protein 1) (Atherin) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 78 ( ENSG00000141858 ) 3 ( ENSG00000288488 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q6SPF0 |
| Gene Card | SAMD1 |
| Uniprot ID | Q6SPF0 |
| Pfam | PF00536 |
| In ASD | no |
| Allosteric Prediction | no (-1.516059238) |
| Ortholog in Animals | Alpaca_ SAMD1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SAMD11, SCMH1, SFMBT2, SAMD7, L3MBTL3, SCML2, THAP10, PHC2, PHC3, PHC1, SFMBT1, SCML1, SAMD13, L3MBTL2, MBTD1, L3MBTL4, L3MBTL1, SCML4 |
| Tissue | NA |
| Tissue Specificity | Expressed in atherosclerotic lesions, not in normal intima. Expressed in foam cells. {ECO:0000269|PubMed:16159594}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6LUI (X-ray 1.78A ) 6LUJ (X-ray 1.12A ) 6LUK (X-ray 2.05A ) |
| DBSNP | rs8062 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:34006929}. Chromosome {ECO:0000269|PubMed:34006929}. Secreted {ECO:0000269|PubMed:16159594, ECO:0000269|PubMed:34006929}. Note=In atherosclerotic lesions, it is found in the extracellular compartment and in foam cells cytoplasm. {ECO:0000269|PubMed:16159594, ECO:0000269|PubMed:34006929}. |
| Mouse PG classification | NA |
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