| Gene Information | |
|---|---|
| Gene Name | SAFB |
| Organism | Homo sapiens (Human) |
| Gene Length | 915 |
| Protein Names | Scaffold attachment factor B1 (SAF-B) (SAF-B1) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE-TATA-binding protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000160633 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q15424 |
| Gene Card | SAFB |
| Uniprot ID | Q15424 |
| Pfam | PF00076; PF02037 |
| In ASD | no |
| Allosteric Prediction | no (-0.139764887) |
| Ortholog in Animals | Alpaca_ SAFB ( ortholog_one2one ) Dog_ SAFB ( ortholog_one2one ) GuineaPig_ SAFB ( ortholog_one2one ) Macaque_ SAFB ( ortholog_one2one ) Mouse_ Safb ( ortholog_one2one ) Pig_ SAFB ( ortholog_one2one ) Rat_ Safb ( ortholog_one2one ) Rabbit_ SAFB ( ortholog_one2one ) |
| Ohnologs | SLTM |
| Paralogs | SLTM, SAFB2 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Expressed at high levels in the CNS and at low levels in the liver. Expressed in a wide number of breast cancer cell lines. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:19674106, ECO:0000269|PubMed:22693546}. |
| Mouse PG classification | NA |
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