Gene Information
Gene NameSAF2
OrganismHomo sapiens (Human)
Gene Length499
Protein NamesSialic acid-binding Ig-like lectin 8 (Siglec-8) (Sialoadhesin family member 2) (SAF-2)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ9NYZ4
Gene CardSIGLEC8
Uniprot IDQ9NYZ4
PfamPF07686
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed specifically on red blood cells namely basophil, mast cells and eosinophils. {ECO:0000269|PubMed:10625619, ECO:0000269|PubMed:10856141}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2N7A  (NMR  2N7B  (NMR 
DBSNP rs10409962  rs3829659 
Subcellular location [CC]Membrane;
Single-pass type I membrane protein.
Mouse PG classificationNA
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