| Gene Information | |
|---|---|
| Gene Name | ZIP4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 647 |
| Protein Names | Zinc transporter ZIP4 (Solute carrier family 39 member 4) (Zrt- and Irt-like protein 4) (ZIP-4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q6P5W5 |
| Gene Card | SLC39A4 |
| Uniprot ID | Q6P5W5 |
| Pfam | PF02535; PF18292 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in kidney, small intestine, stomach, colon, jejunum and duodenum. {ECO:0000269|PubMed:12032886, ECO:0000269|PubMed:12068297}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2280839 rs2280838 rs117535951 rs121434292 rs121434290 rs17855765 rs1871533 rs121434287 rs2977838 rs7823979 rs121434293 rs782110796 rs121434291 rs2272662 rs1871534 rs121434289 rs121434288 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:14612438}; Multi-pass membrane protein {ECO:0000269|PubMed:14612438}. Recycling endosome membrane {ECO:0000269|PubMed:14612438}; Multi-pass membrane protein {ECO:0000269|PubMed:14612438}. Note=Colocalized with TFRC in the recycling endosomes. Cycles between endosomal compartments and the plasma membrane in response to zinc availability. |
| Mouse PG classification | NA |
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