| Gene Information | |
|---|---|
| Gene Name | FNDC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1894 |
| Protein Names | Fibronectin type III domain-containing protein 1 (Activation-associated cDNA protein) (Expressed in synovial lining protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000164694 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q4ZHG4 |
| Gene Card | FNDC1 |
| Uniprot ID | Q4ZHG4 |
| Pfam | PF00041 |
| In ASD | no |
| Allosteric Prediction | no (-1.031837826) |
| Ortholog in Animals | Alpaca_ FNDC1 ( ortholog_one2one ) Dog_ FNDC1 ( ortholog_one2one ) GuineaPig_ FNDC1 ( ortholog_one2one ) Macaque_ FNDC1 ( ortholog_one2one ) Mouse_ Fndc1 ( ortholog_one2one ) Pig_ FNDC1 ( ortholog_one2one ) Rat_ Fndc1 ( ortholog_one2one ) Rabbit_ FNDC1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ABI3BP |
| Tissue | adipose.tissue, gall.bladder, smooth.muscle, thyroid |
| Tissue Specificity | Almost absent from healthy skin; especially in epidermal keratinocytes, skin fibroblasts or endothelial cells and is barely detectable in benign melanocytic naevi. Expressed in the stroma close to skin tumors, in the tumor cells themselves and in the epidermis of psoriasis. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs509648 rs420137 rs370434 rs420054 rs3003174 rs2501176 rs3842694 rs386360 rs7763726 |
| Subcellular location [CC] | Secreted {ECO:0000305}. |
| Mouse PG classification | NA |
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