| Gene Information | |
|---|---|
| Gene Name | TMEM176B |
| Organism | Homo sapiens (Human) |
| Gene Length | 270 |
| Protein Names | Transmembrane protein 176B (Protein LR8) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 244 ( ENSG00000106565 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q3YBM2 |
| Gene Card | TMEM176B |
| Uniprot ID | Q3YBM2 |
| Pfam | PF04103 |
| In ASD | no |
| Allosteric Prediction | no (-1.795019203) |
| Ortholog in Animals | Alpaca_ TMEM176B ( ortholog_one2many ) Dog_ TMEM176B ( ortholog_one2one ) Macaque_ TMEM176B ( ortholog_one2one ) Mouse_ Tmem176b ( ortholog_one2one ) Pig_ TMEM176B ( ortholog_one2one ) Rat_ Tmem176b ( ortholog_one2one ) Rabbit_ TMEM176B ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TMEM176A |
| Tissue | NA |
| Tissue Specificity | Expressed in lung and dermal fibroblasts. {ECO:0000269|PubMed:9922225}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs10240587 rs11546671 rs28434777 rs3173833 rs2072443 rs17256042 |
| Subcellular location [CC] | Nucleus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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