| Gene Information | |
|---|---|
| Gene Name | CYP4V2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 525 |
| Protein Names | Cytochrome P450 4V2 (Docosahexaenoic acid omega-hydroxylase CYP4V2) (EC 1.14.14.79) (Long-chain fatty acid omega-monooxygenase) (EC 1.14.14.80) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000145476 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q6ZWL3 |
| Gene Card | CYP4V2 |
| Uniprot ID | Q6ZWL3 |
| Pfam | PF00067 |
| In ASD | no |
| Allosteric Prediction | no (-0.958566874) |
| Ortholog in Animals | Alpaca_ CYP4V2 ( ortholog_one2one ) Dog_ CYP4V2 ( ortholog_one2one ) GuineaPig_ CYP4V2 ( ortholog_one2one ) Macaque_ CYP4V2 ( ortholog_one2one ) Mouse_ Cyp4v3 ( ortholog_one2one ) Pig_ CYP4V2 ( ortholog_one2one ) Rat_ Cyp4v3 ( ortholog_one2one ) Rabbit_ CYP4V2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CYP4F12, CYP4A22, CYP4A11, CYP4B1, CYP4F8, CYP4F11, CYP19A1, CYP4F2, CYP4F22, CYP4X1, CYP4Z1, CYP4F3 |
| Tissue | NA |
| Tissue Specificity | Broadly expressed. Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, retina, retinal pigment epithelium (RPE) and lymphocytes. {ECO:0000269|PubMed:15042513, ECO:0000269|PubMed:22772592}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1055138 rs119103282 rs119103285 rs199476185 rs119103283 rs149684063 rs34331648 rs13146272 rs34745240 rs199476197 rs199476199 rs61755911 rs72646291 rs119103284 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:22772592}; Single-pass membrane protein {ECO:0000305}. |
| Mouse PG classification | HPG |
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