| Gene Information | |
|---|---|
| Gene Name | S100A7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 101 |
| Protein Names | Protein S100-A7 (Psoriasin) (S100 calcium-binding protein A7) |
| Target Name | protein s100-a7 |
| Target Type | NA |
| Gene Age | 55 ( ENSG00000143556 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P31151 |
| Gene Card | S100A7 |
| Uniprot ID | P31151 |
| Pfam | PF01023 |
| In ASD | no |
| Allosteric Prediction | no (-0.337208749) |
| Ortholog in Animals | Alpaca_ S100A7 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | S100A7A, S100A3, S100A10, S100A4, SNTN, S100A8, S100A13, S100A11, S100A5, S100B, S100A14, S100A16, S100Z, S100A1, S100A12, S100P, S100G, S100A2, CRNN, S100A9, S100A6 |
| Tissue | skin, tonsil, esophagus.mucosa, lower.leg.skin, suprapubic.skin, vagina |
| Tissue Specificity | Fetal ear, skin, and tongue and human cell lines. Highly up-regulated in psoriatic epidermis. Also highly expressed in the urine of bladder squamous cell carcinoma (SCC) bearing patients. {ECO:0000269|PubMed:8618345}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1PSR (X-ray 1.05A ) 2PSR (X-ray 2.05A ) 2WND (X-ray 1.60A ) 2WOR (X-ray 1.70A ) 2WOS (X-ray 1.70A ) 3PSR (X-ray 2.50A ) 4AQJ (X-ray 1.60A ) |
| DBSNP | rs3014837 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:8618345}. Secreted {ECO:0000269|PubMed:8618345}. Note=Secreted by a non-classical secretory pathway. |
| Mouse PG classification | NA |
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