| Gene Information | |
|---|---|
| Gene Name | SLC49A4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 478 |
| Protein Names | Solute carrier family 49 member 4 (Disrupted in renal cancer protein 2) (Disrupted in renal carcinoma protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000138463 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q96SL1 |
| Gene Card | SLC49A4 |
| Uniprot ID | Q96SL1 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.850969512) |
| Ortholog in Animals | Alpaca_ SLC49A4 ( ortholog_one2one ) Dog_ SLC49A4 ( ortholog_one2one ) GuineaPig_ SLC49A4 ( ortholog_one2one ) Macaque_ SLC49A4 ( ortholog_one2one ) Mouse_ Slc49a4 ( ortholog_one2one ) Pig_ SLC49A4 ( ortholog_one2one ) Rat_ Slc49a4 ( ortholog_one2one ) Rabbit_ SLC49A4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SLC49A3, FLVCR1, FLVCR2, CFAP276 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Expressed in proximal tubular cells of the kidney. {ECO:0000269|PubMed:11912179}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Lysosome membrane {ECO:0000269|PubMed:21692750}; Multi-pass membrane protein {ECO:0000269|PubMed:21692750}. |
| Mouse PG classification | NA |
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