| Gene Information | |
|---|---|
| Gene Name | SLC1A2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 574 |
| Protein Names | Excitatory amino acid transporter 2 (Glutamate/aspartate transporter II) (Sodium-dependent glutamate/aspartate transporter 2) (Solute carrier family 1 member 2) |
| Target Name | excitatory amino acid transporter 2 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000110436 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P43004 |
| Gene Card | SLC1A2 |
| Uniprot ID | P43004 |
| Pfam | PF00375 |
| In ASD | yes |
| Allosteric Prediction | yes (1.000267776) |
| Ortholog in Animals | Alpaca_ SLC1A2 ( ortholog_one2one ) Dog_ SLC1A2 ( ortholog_one2one ) GuineaPig_ SLC1A2 ( ortholog_one2one ) Macaque_ SLC1A2 ( ortholog_one2one ) Mouse_ Slc1a2 ( ortholog_one2one ) Pig_ SLC1A2 ( ortholog_one2one ) Rat_ Slc1a2 ( ortholog_one2one ) Rabbit_ SLC1A2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SLC1A4, SLC1A6, SLC1A7, SLC1A1, SLC1A5, SLC1A3 |
| Tissue | brain, cerebral.cortex |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7VR7 (EM 2.80A ) 7VR8 (EM 3.20A ) 7XR4 (EM 3.40A ) 7XR6 (EM 3.40A ) |
| DBSNP | rs886037942 rs886037943 rs781379291 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:14506254, ECO:0000269|PubMed:15265858, ECO:0000269|PubMed:26690923, ECO:0000269|PubMed:7521911}; Multi-pass membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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