| Gene Information | |
|---|---|
| Gene Name | RUFY2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 606 |
| Protein Names | RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000204130 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8WXA3 |
| Gene Card | RUFY2 |
| Uniprot ID | Q8WXA3 |
| Pfam | PF01363; PF02759 |
| In ASD | no |
| Allosteric Prediction | no (-1.306471387) |
| Ortholog in Animals | Alpaca_ RUFY2 ( ortholog_one2one ) Dog_ RUFY2 ( ortholog_one2one ) GuineaPig_ RUFY2 ( ortholog_one2one ) Macaque_ RUFY2 ( ortholog_one2one ) Mouse_ Rufy2 ( ortholog_one2one ) Pig_ RUFY2 ( ortholog_one2one ) Rat_ Rufy2 ( ortholog_one2one ) Rabbit_ RUFY2 ( ortholog_one2one ) |
| Ohnologs | RUFY3, RUFY1 |
| Paralogs | RUFY1, PLEKHF1, ZFYVE1, ZFYVE26, ZFYVE28, RUNDC3B, PLEKHM2, RUFY3, RUNDC3A, ZFYVE16, PLEKHF2, SNX29, ZFYVE19 |
| Tissue | NA |
| Tissue Specificity | Expressed in brain, lung and testis. {ECO:0000269|PubMed:11877430}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11816774 |
| Subcellular location [CC] | Nucleus {ECO:0000250}. |
| Mouse PG classification | NA |
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