| Gene Information | |
|---|---|
| Gene Name | GORASP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 452 |
| Protein Names | Golgi reassembly-stacking protein 2 (GRS2) (Golgi phosphoprotein 6) (GOLPH6) (Golgi reassembly-stacking protein of 55 kDa) (GRASP55) (p59) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000115806 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9H8Y8 |
| Gene Card | GORASP2 |
| Uniprot ID | Q9H8Y8 |
| Pfam | PF04495 |
| In ASD | no |
| Allosteric Prediction | no (-0.853928069) |
| Ortholog in Animals | Alpaca_ GORASP2 ( ortholog_one2one ) Dog_ GORASP2 ( ortholog_one2one ) GuineaPig_ GORASP2 ( ortholog_one2one ) Macaque_ GORASP2 ( ortholog_one2one ) Mouse_ Gorasp2 ( ortholog_one2one ) Pig_ GORASP2 ( ortholog_one2one ) Rat_ Gorasp2 ( ortholog_one2one ) Rabbit_ GORASP2 ( ortholog_one2one ) |
| Ohnologs | GORASP1 |
| Paralogs | GORASP1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.03637(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3RLE (X-ray 1.65A ) 4EDJ (X-ray 1.90A ) |
| DBSNP | rs3770436 |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000269|PubMed:10487747, ECO:0000269|PubMed:11101516, ECO:0000269|PubMed:27062250}; Lipid-anchor {ECO:0000269|PubMed:11101516}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:27062250}. Golgi apparatus {ECO:0000269|PubMed:28067262}. Note=Detected in the intermediate Golgi, membrane-associated (By similarity). ER stress triggers its relocalization from Golgi to ER membrane (PubMed:27062250, PubMed:28067262). {ECO:0000250|UniProtKB:Q9R064, ECO:0000269|PubMed:27062250, ECO:0000269|PubMed:28067262}. |
| Mouse PG classification | NA |
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