| Gene Information | |
|---|---|
| Gene Name | EAPP |
| Organism | Homo sapiens (Human) |
| Gene Length | 285 |
| Protein Names | E2F-associated phosphoprotein (EAPP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000129518 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q56P03 |
| Gene Card | EAPP |
| Uniprot ID | Q56P03 |
| Pfam | PF10238 |
| In ASD | no |
| Allosteric Prediction | no (-0.670386314) |
| Ortholog in Animals | Alpaca_ EAPP ( ortholog_one2one ) Dog_ EAPP ( ortholog_one2one ) Macaque_ EAPP ( ortholog_one2one ) Mouse_ Eapp ( ortholog_one2one ) Pig_ EAPP ( ortholog_one2one ) Rat_ Eapp ( ortholog_one2one ) Rabbit_ EAPP ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. Highest levels in heart, placenta, skeletal muscle and pancreas. Lower levels in brain, lung and kidney. In the brain, expressed in all regions with high levels in the cerebellum and cerebral cortex. Expressed in COS1 and transformed skin fibroblasts. {ECO:0000269|PubMed:15716352, ECO:0000269|PubMed:15820313}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.055556(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17352411 |
| Subcellular location [CC] | Cytoplasm. Nucleus. |
| Mouse PG classification | NA |
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