| Gene Information | |
|---|---|
| Gene Name | GPR78 |
| Organism | Homo sapiens (Human) |
| Gene Length | 363 |
| Protein Names | G-protein coupled receptor 78 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 55 ( ENSG00000155269 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96P69 |
| Gene Card | GPR78 |
| Uniprot ID | Q96P69 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | yes (0.456424011) |
| Ortholog in Animals | Alpaca_ GPR78 ( ortholog_one2one ) Macaque_ GPR78 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | GPR63, GPR45, GPR26 |
| Tissue | placenta |
| Tissue Specificity | High level of expression in placenta. Expressed throughout the brain at low level. No expression detected in skeletal muscle, lung, heart, liver, pancreas, or kidney. {ECO:0000269|PubMed:17363172}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17844778 rs11941659 rs9685931 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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