| Gene Information | |
|---|---|
| Gene Name | RRP8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 456 |
| Protein Names | Ribosomal RNA-processing protein 8 (EC 2.1.1.-) (Cerebral protein 1) (Nucleomethylin) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000132275 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O43159 |
| Gene Card | RRP8 |
| Uniprot ID | O43159 |
| Pfam | PF05148 |
| In ASD | no |
| Allosteric Prediction | yes (0.297982308) |
| Ortholog in Animals | Alpaca_ RRP8 ( ortholog_one2one ) Dog_ RRP8 ( ortholog_one2one ) GuineaPig_ RRP8 ( ortholog_one2one ) Macaque_ RRP8 ( ortholog_one2one ) Mouse_ Rrp8 ( ortholog_one2one ) Pig_ RRP8 ( ortholog_one2one ) Rat_ Rrp8 ( ortholog_one2one ) Rabbit_ RRP8 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001657(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2ZFU (X-ray 2.00A ) |
| DBSNP | rs11040934 rs17834692 |
| Subcellular location [CC] | Nucleus, nucleolus {ECO:0000269|PubMed:11790298, ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:18485871}. Note=Localizes at rDNA locus. |
| Mouse PG classification | NA |
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