| Gene Information | |
|---|---|
| Gene Name | ST3GAL3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 375 |
| Protein Names | CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase (EC 2.4.3.6) (Beta-galactoside alpha-2,3-sialyltransferase 3) (Alpha 2,3-ST 3) (Gal beta-1,3(4) GlcNAc alpha-2,3 sialyltransferase) (N-acetyllactosaminide alpha-2,3-sialyltransferase) (ST3Gal III) (ST3GalIII) (ST3N) (Sialyltransferase 6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000126091 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q11203 |
| Gene Card | ST3GAL3 |
| Uniprot ID | Q11203 |
| Pfam | PF00777 |
| In ASD | no |
| Allosteric Prediction | no (-1.071327563) |
| Ortholog in Animals | Alpaca_ ST3GAL3 ( ortholog_one2one ) Dog_ ST3GAL3 ( ortholog_one2one ) GuineaPig_ ST3GAL3 ( ortholog_one2one ) Macaque_ ST3GAL3 ( ortholog_one2one ) Mouse_ St3gal3 ( ortholog_one2one ) Pig_ ST3GAL3 ( ortholog_one2one ) Rat_ St3gal3 ( ortholog_one2one ) Rabbit_ ST3GAL3 ( ortholog_one2one ) |
| Ohnologs | ST3GAL6 |
| Paralogs | ST6GALNAC5, C20orf173, ST3GAL4, ST3GAL2, ST6GAL1, ST6GALNAC4, ST6GALNAC3, ST6GALNAC6, ST6GALNAC2, ST3GAL5, ST3GAL6, ST6GAL2, ST6GALNAC1, ST3GAL1 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in adult skeletal muscle and in all fetal tissues examined and to a much lesser extent in placenta, lung and liver. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs387906943 |
| Subcellular location [CC] | Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted. Note=Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid. |
| Mouse PG classification | NA |
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