| Gene Information | |
|---|---|
| Gene Name | RRP1B |
| Organism | Homo sapiens (Human) |
| Gene Length | 758 |
| Protein Names | Ribosomal RNA processing protein 1 homolog B (RRP1-like protein B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000160208 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q14684 |
| Gene Card | RRP1B |
| Uniprot ID | Q14684 |
| Pfam | PF05997 |
| In ASD | no |
| Allosteric Prediction | no (-0.683345087) |
| Ortholog in Animals | Alpaca_ RRP1B ( ortholog_one2one ) Dog_ RRP1B ( ortholog_one2one ) GuineaPig_ RRP1B ( ortholog_one2one ) Macaque_ RRP1B ( ortholog_one2one ) Mouse_ Rrp1b ( ortholog_one2one ) Pig_ RRP1B ( ortholog_one2one ) Rat_ Rrp1b ( ortholog_one2one ) Rabbit_ RRP1B ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RRP1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.009904(Chimpanzee);0.012448(Mouse);0.001872(Rat);0.035294(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs9306160 |
| Subcellular location [CC] | Nucleus, nucleolus {ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:20040599, ECO:0000269|PubMed:20926688, ECO:0000269|PubMed:26311876}. Nucleus, nucleoplasm {ECO:0000269|PubMed:20926688}. Chromosome {ECO:0000269|PubMed:19710015}. Note=Predominantly located in the nucleolus with a small amount found in the nucleoplasm (PubMed:20926688). Associates with the perichromatin region during metaphase and with cytoplasmic foci during telophase before reaccumulation in the nucleolus during G2 (PubMed:20926688). Associates with heterochromatin and euchromatin (PubMed:19710015). {ECO:0000269|PubMed:19710015, ECO:0000269|PubMed:20926688}.; Nucleus, nucleoplasm {ECO:0000269|PubMed:26311876}. Note=(Microbial infection) Following infection by influenza A virus, partially translocates from the nucleolus to the nucleoplasm. {ECO:0000269|PubMed:26311876}. |
| Mouse PG classification | NA |
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