| Gene Information | |
|---|---|
| Gene Name | RRM1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 792 |
| Protein Names | Ribonucleoside-diphosphate reductase large subunit (EC 1.17.4.1) (Ribonucleoside-diphosphate reductase subunit M1) (Ribonucleotide reductase large subunit) |
| Target Name | rrm1 messenger rna |
| Target Type | Discontinued target |
| Gene Age | 454 ( ENSG00000167325 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P23921 |
| Gene Card | RRM1 |
| Uniprot ID | P23921 |
| Pfam | PF03477; PF02867; PF00317 |
| In ASD | yes |
| Allosteric Prediction | yes (0.999882884) |
| Ortholog in Animals | Alpaca_ RRM1 ( ortholog_one2one ) Dog_ RRM1 ( ortholog_one2one ) GuineaPig_ RRM1 ( ortholog_one2one ) Macaque_ RRM1 ( ortholog_one2one ) Mouse_ Rrm1 ( ortholog_one2one ) Pig_ RRM1 ( ortholog_one2one ) Rat_ Rrm1 ( ortholog_one2one ) Rabbit_ RRM1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.053333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2WGH (X-ray 2.30A ) 3HNC (X-ray 2.41A ) 3HND (X-ray 3.21A ) 3HNE (X-ray 3.11A ) 3HNF (X-ray 3.16A ) 4X3V (X-ray 3.70A ) 5D1Y (X-ray 9.01A ) 5TUS (X-ray 2.66A ) 6AUI (EM 3.30A ) 6L3R (X-ray 2.00A ) 6L7L (X-ray 2.17A ) 6LKM (X-ray 2.55A ) |
| DBSNP | rs2228123 rs2229196 |
| Subcellular location [CC] | Cytoplasm. |
| Mouse PG classification | NA |
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