| Gene Information | |
|---|---|
| Gene Name | RRAD |
| Organism | Homo sapiens (Human) |
| Gene Length | 308 |
| Protein Names | GTP-binding protein RAD (RAD1) (Ras associated with diabetes) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000166592 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P55042 |
| Gene Card | RRAD |
| Uniprot ID | P55042 |
| Pfam | PF00071 |
| In ASD | no |
| Allosteric Prediction | no (-0.67063496) |
| Ortholog in Animals | Alpaca_ RRAD ( ortholog_one2one ) Dog_ RRAD ( ortholog_one2one ) GuineaPig_ RRAD ( ortholog_one2one ) Macaque_ RRAD ( ortholog_one2one ) Mouse_ Rrad ( ortholog_one2one ) Pig_ RRAD ( ortholog_one2one ) Rat_ Rrad ( ortholog_one2one ) Rabbit_ RRAD ( ortholog_one2one ) |
| Ohnologs | REM1, REM2, GEM |
| Paralogs | RRAS, RHEB, KRAS, DIRAS1, RRAS2, RAP2B, HRAS, RERG, RASL12, RIT1, DIRAS2, ERAS, NKIRAS1, RALB, RASD2, GEM, DIRAS3, MRAS, RAP2A, RASD1, REM1, NKIRAS2, RALA, RAP1A, RASL11B, RAP1B, RASL10A, RASL11A, REM2, RERGL, RIT2, RHEBL1, NRAS, RAP2C, RASL10B |
| Tissue | heart, lung |
| Tissue Specificity | Most abundantly expressed in the heart. Also found in the skeletal muscle and lung. Lesser amounts in placenta and kidney. Also detected in adipose tissue. Overexpressed in muscle of type II diabetic humans. {ECO:0000269|PubMed:18056528}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2DPX (X-ray 1.80A ) 2GJS (X-ray 1.90A ) 3Q72 (X-ray 1.66A ) 3Q7P (X-ray 2.50A ) 3Q7Q (X-ray 2.30A ) |
| DBSNP | rs7198458 |
| Subcellular location [CC] | Cell membrane {ECO:0000250}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |